SnapShot: Tumor Angiogenesis
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چکیده
منابع مشابه
SnapShot: Tumor Angiogenesis
Pericyte Endothelial cell (EC) Basement membrane Tumor cells co-opt pre-existing vessels Tumor cells line tumor vessels Cancer stem-like cells differentiate to ECs Endothelial progenitor cell (EPC) differentiates to EC How do tumors recruit blood vessels? How does anti-angiogenic therapy work? See online version for legend and references.
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متن کاملangiogenesis and tumor
angiogenesis, the process of new blood vessel formation from existing ones, plays an important role in the physiologic circumstances such as embryonic development, placenta formation, and wound healing. it is also crucial to progress of pathogenic processes of a variety of disorders, including tumor growth and metastasis. in general, angiogenesis process is a multi-factorial and highly structu...
متن کاملTumor Angiogenesis
The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that occurs in physiological situations, whereas others are interested in angiogenesis that dominates pathological conditions. These efforts have l...
متن کاملTumor Angiogenesis
In a seminal New England Journal of Medicine article, published 40 years ago, Folkman proposed the concept that angiogenesis could be a target for cancer therapy [1]. This proposal emerged from early observations that some tumors cells were capable of stimulating endothelial cells to form new capillary sprouts and that nonvascularized tumors were held in a dormant state, unable to grow beyond a...
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ژورنال
عنوان ژورنال: Cell
سال: 2012
ISSN: 0092-8674
DOI: 10.1016/j.cell.2012.05.025